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Bitter gourd extract, a common dietary supplement, exerts a significant effect against breast cancercell growth and may eventually become a chemopreventive agent against breast cancer, according to a recent study.
“Our findings suggest that bitter gourd extract modulates several signal pathways that induces breast cancer cell death,” said researcher Ratna Ray, professor in Department of Pathology at Saint Louis University. “This extract can be utilised as a dietary supplement for the prevention of breast cancer.”
Results of this study are published in Cancer Research, a journal of the American Association for Cancer Research.
Previous research has shown Momordica charantia, also known as bitter gourd and bitter melon, to have hypoglycemic and hypolipidemic effects, according to Ray. Because of these effects, the extract is commonly used in folk medicines as a remedy for diabetes in locales such as India, China and Central America, according to the researchers.
Using human breast cancer cells and primary human mammary epithelial cells in a lab, Ray and colleagues found the mechanism of bitter melon extract significantly decreased proliferation, that is, cell growth and division, and induced death in breast cancer cells. These early results offer an encouraging path for research into breast cancer.
“Breast cancer is a major killer among women around the world, and in that perspective, results from this study are quite significant,” said Rajesh Agarwal, professor in the Department of Pharmaceutical Sciences at the University of Colorado, Denver School of Pharmacy.
“This study may provide us with one more agent that could be used against breast cancer if additional studies hold true.” According to Agarwal, the Cancer Research associate editor for this study, the simple design, clear-cut results and the importance of these findings in breast cancer prevention makes this different from previous research.
Smile at each other, smile at your wife, smile at your husband, smile at your children, smile at each other - it doesn't matter who it is - and that will help you to grow up in greater love for each other. ~ Mother Teresa
Each New Year, we wish others happiness and prosperity. What really is the sign of prosperity? There are several - a smile, contentment, freedom, the willingness to share, fearlessness and the trust and confidence that you will get what you need in life.
Welcome the New Year with a genuine smile. As you flip the calendar, keep flipping your mind as well. Don’t fill your future dates with past events. Learn and unlearn from the past, and move on.
You want to be free of greed, hatred, jealousy and all such imperfections. Understand that negative emotions are due to the past. Do not let the past affect your life in the present. If you cannot forgive the past, then your future will be miserable. This New Year make up with someone with whom you are not on good terms. Start life afresh.
In the New Year, wish peace and prosperity for all. Do selfless service. Live your life well. Realise that your priority is to check violence in the world, free of domestic and societal violence. Make a resolution to do more good, help people in need and bring solace to those suffering.
Whenever you are useful to people, merit will never be lost. Any good gesture or action of yours will always come back to you. Today you have the whole world for a family. That’s what you need to feel, that everybody is part of your own family. Take responsibility. Then there is no suffering.
The spiritual dimension of life brings a great sense of belongingness, responsibility, compassion and caring for the whole world, for all life. In its truest form spirituality helps us overcome narrow boundaries of caste, creed, religion and nationality and give you a broader awareness of life everywhere.
Open your eyes and see how much you have been given.
Focus on what you have rather than what you don’t have.
The more grateful you are, the more will be given to you.
Conversely, the more you complain, the more will be taken away from you. This is what Jesus Christ meant when he said, “Those who have will be given more; those who don’t give, and even what they have will be taken away from them.”
With gratitude, reach out and help those who are less endowed. You will get much contentment when you serve selflessly. Then you realise that your problems aren’t so big after all. The biggest reason for mental depression is the constant refrain of the mind that says, “What about me?” This is a sign of lack of prosperity.
Become free like a bird. Open your wings and learn to fly. This is something you have to experience within yourself. If you think you are in bondage, you will remain bound here. Be free. When will you experience freedom? After you die? Become free right now. Sit down and become contented. Spend some time in meditation and satsang. This not only calms your mind, your inner self becomes strong enough to deal with challenges.
When the mind relaxes, the intellect becomes sharp. When the mind is loaded with ambitions and feverish desires, then the intellect loses its keenness. When intellect and observation are not sharp, life does not express itself fully. Ideas don’t flow properly and abilities diminish day by day. With this understanding, you step out of your narrow confines and that will solve many of the problems in your life. When you are centred, there is happiness always. With this calmness, talents arise naturally. Intuition comes, beauty comes, peace comes; Love springs up. Prosperity comes.
A diverse group of senior citizens offered insights that came down to these five points:
Be true to yourself by living with intention. Know your heart's desire and seek it.
Live it with no regrets. Regrets are feared more than death. So mend fences, make peace. Take chances, pursue those dreams, and accept failure as well. Rather than be crushed by failure, learn from it.
Become love. Love is not an emotion but a choice; a way of being that involves seeing ourselves and others with kindness and compassion. That love creates the opportunities to follow your bliss, heal wounds in yourself and others, and to find peace despite challenges and hardships.
Live in the moment. Right here, right. That's all.
Give more than you take. Find yourself and then lose yourself. Once you identify your heart's desire and live your life pursuing it, the chance of accumulating any regrets is reduced. Once you become love, kindness becomes part of your purpose, and each moment offers all the joy of a lifetime. This creates an abundance of resources in the form of love. trust, hope, joy, kindness, and compassion. Draw from this deep well and give it away. Leave the campsite better better than you found it, as one wise elder put it.
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